ileocecal fold, two flaps surrounding the opening of the ileum into the large intestine where the cecum and ascending colon join together. The flaps project into the lumen of the large intestine and come together at their end, forming ridges. Musculature from the ileum continues into each flap, forming a sphincter. Possible functions of the ileocecal fold include preventing reflux from the cecum to the ileum and regulating the passage of contents from the ileum to the cecum.