hypolipoproteinemia /hī′pōlip′ōprō′tēnē″mē·ə/ [Gk, hypo + lipos, fat, proteios, first rank, haima, blood] , a group of defects of lipoprotein metabolism that cause varying complexes of signs. Primary, or hereditary, hypolipoproteinemia factors include abnormal transport of triglycerides in the blood, low levels of high-density lipoproteins, and abnormal fat deposits in the body, especially in the kidneys and the liver. In some of the syndromes ocular, cardiovascular intestinal, and neurological effects are also present. The condition also may be secondary to anemia, malabsorption syndromes, or malnutrition. Also called hypolipidemia. Kinds include abetalipoproteinemia, familial hypocalphalipoproteinemia, hypobetalipoproteinemia, lecithin-cholesterol acetyltransferase (LCAT) deficiency, Tangier disease.
