hemoglobin C disease, an inherited hemoglobinopathy caused by hemoglobin C. The heterozygous form is asymptomatic; homozygous hemoglobin C disease causes a mild to moderate hemolytic anemia. In the homozygous form, target cells and hemoglobin C crystals are seen in microscopic examination of a blood film. See also hemoglobin C, hemoglobin SC (Hb SC) disease.
