gentamicin sulfate /jen′təmī″sin/ , an aminoglycoside antibiotic. ▪ INDICATIONS: It is prescribed for the treatment of severe infections caused by organisms sensitive to gentamicin, especially gram-negative organisms. ▪ CONTRAINDICATIONS: Concomitant administration of other potentially ototoxic or nephrotoxic drugs or known hypersensitivity to this drug or to other aminoglycoside medications prohibits its use. It is used with caution in patients with impaired renal function. It cannot be coadministered with a variety of other drugs, including penicillins. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are nephrotoxicity, auditory or vestibular ototoxicity, impairment of neuromuscular transmission, and hypersensitivity reactions.
