griseofulvin /gris′ē·ōful″vin/ , an antifungal drug. ▪ INDICATIONS: It is prescribed in the treatment of certain fungal infections of the skin, hair, and nails. ▪ CONTRAINDICATIONS: Liver dysfunction, porphyria, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: The most serious adverse effects are blood dyscrasias. Headache, GI symptoms, and rashes also may occur.