Alström’s syndrome [Carl Henry Alström, Swedish geneticist, 1907–1993] , an inherited disease characterized by multiple system resistance to hormones. Clinical features include retinal degeneration leading to childhood blindness, type 2 diabetes mellitus, infantile obesity, nerve deafness, baldness, hyperuricemia, and hypertriglyceridemia. Males may also have high plasma gonadotropin levels and hypogonadism. The condition is transmitted through an autosomal-recessive gene.