alprazolam /alpraz″ələm/ , a benzodiazepine antianxiety agent. ▪ INDICATIONS: It is prescribed in the treatment of anxiety disorders or the short-term relief of the symptoms of anxiety. ▪ CONTRAINDICATIONS: Acute narrow-angle glaucoma or known sensitivity to this drug or other benzodiazepines prohibits its use. It is contraindicated with ketoconazole and itraconazole. Pregnancy is also a contraindication. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are drowsiness, light-headedness, and tolerance or physical dependence.