fosamprenavir, an antiretroviral drug. ▪ INDICATIONS: This drug is used in combination with other antiretrovirals to treat HIV-1 infection. ▪ CONTRAINDICATIONS: Known hypersensitivity to protease inhibitors prohibits the use of this drug. ▪ ADVERSE EFFECTS: Adverse effects of this drug include rash, pruritus, headache, fatigue, depression, oral paresthesia, and redistribution or accumulation of body fat. Common side effects include nausea, diarrhea, vomiting, and abdominal pain.