follitropin alfa/follitropin beta, an ovulation stimulant. ▪ INDICATIONS: It is used to induce ovulation during assisted reproductive technologies such as in vitro fertilization. ▪ CONTRAINDICATIONS: Factors that prohibit its use include known hypersensitivity, pregnancy, undiagnosed vaginal bleeding, intracranial lesion, and ovarian cyst not caused by polycystic ovarian disease. ▪ ADVERSE EFFECTS: Life-threatening effects are birth defects and spontaneous abortion. Other adverse effects include malaise, nausea, vomiting, constipation, increased appetite, abdominal pain, rash, dermatitis, urticaria, alopecia, polyuria, urinary frequency, multiple ovulation, and breast pain.