fluvastatin, an antilipidemic drug. ▪ INDICATIONS: It is used as an adjunct treatment in primary hypercholesterolemia (types Ia and Ib) and in coronary atherosclerosis associated with coronary artery disease. ▪ CONTRAINDICATIONS: Factors that prohibit its use include known hypersensitivity to this drug, pregnancy, lactation, and active liver disease. ▪ ADVERSE EFFECTS: Life-threatening effects are liver dysfunction, myositis, rhabdomyolysis, thrombocytopenia, hemolytic anemia, and leukopenia. Other adverse effects include rash, pruritus, nausea, constipation, diarrhea, dyspepsia, flatus, pancreatitis, lens opacities, myalgia, headache, dizziness, insomnia, fatigue, influenza, upper respiratory infection, rhinitis, cough, pharyngitis, and sinusitis.
