exemestane, an antineoplastic drug. ▪ INDICATIONS: It is used to treat advanced breast cancer in postmenopausal patients whose cancer is unresponsive to other therapies. ▪ CONTRAINDICATIONS: Its use is prohibited in premenopausal women, pregnant women, and clients with known hypersensitivity to this drug. ▪ ADVERSE EFFECTS: Adverse effects include fatigue, diarrhea, constipation, abdominal pain, increased appetite, hypertension, depression, insomnia, anxiety, cough, and dyspnea. Common side effects include nausea, vomiting, hot flashes, and headache.