estramustine phosphate sodium /es′trəmus″tēn/ , an antineoplastic agent. ▪ INDICATIONS: It is prescribed for palliative treatment of metastatic or progressive carcinoma of the prostate. ▪ CONTRAINDICATIONS: Thromboembolytic disorders or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: The most serious adverse effects are cerebrovascular accident, myocardial infarction, thrombophlebitis, pulmonary emboli, and congestive heart failure.
