erythropoiesis /erith′rōpō·ē″sis/ [Gk, erythros + poiein, to make] , the process of erythrocyte production in the bone marrow involving the maturation of a nucleated precursor into a hemoglobin-filled, nucleus-free erythrocyte that is regulated by erythropoietin, a hormone produced by the kidney. Compare erythrogenesis. See also erythrocyte, erythropoietin, hemoglobin, leukopoiesis. −erythropoietic, adj.