eptifibatide, an antiplatelet agent. ▪ INDICATIONS: It is used to treat acute coronary syndrome, including patients with percutaneous coronary intervention. ▪ CONTRAINDICATIONS: The following factors prohibit its use: known hypersensitivity to this drug, active internal bleeding, history of bleeding, stroke within 1 month, major surgery with severe trauma, severe hypotension, history of intracranial bleeding, intracranial neoplasm, arteriovenous malformation/aneurysm, aortic dissection, and dependence on renal dialysis. ▪ ADVERSE EFFECTS: Life-threatening effects of this drug are stroke and bleeding. Hypotension is another serious adverse reaction.