Dubin-Johnson syndrome

Dubin-Johnson syndrome /do̅o̅″bin jon″sən/ [Isadore N. Dubin, American pathologist, 1913–1980; Frank B. Johnson, American pathologist, b. 1919] , a rare chronic hereditary hyperbilirubinemia, characterized by nonhemolytic jaundice, abnormal liver pigmentation, and abnormal function of the gallbladder. It is caused by inability of the liver to excrete several organic anions. See also hyperbilirubinemia of the newborn, Rotor’s syndrome.