dronabinol /drōnab″inol/ , an oral antiemetic that is a synthetic derivative of THC, the principal psychotropic constituent of marijuana. ▪ INDICATIONS: It is prescribed for the treatment of refractory nausea and vomiting caused by cancer chemotherapy. ▪ CONTRAINDICATIONS: It should not be given to persons with known hypersensitivity to the drug or to tetrahydrocannabinol, its active ingredient. ▪ ADVERSE EFFECTS: Among adverse effects reported are drowsiness, dizziness, impaired coordination, and hallucinations. Dronabinol is a Schedule III controlled substance with a high potential for abuse. It can produce both physical and psychological dependence. It is not recommended for patients who are using a central nervous system depressant or other psychoactive drugs.
