doripenem, a miscellaneous antibiotic. ▪ INDICATIONS: This drug is used to treat serious infections caused by Acinetobacter baumannii, Bacteroides caccae, B. fragilis, B. thetaiotaomicron, B. uniformis, B. vulgates, Escherichia coli, Klebsiella pneumoniae, Peptostreptococcus micros, Proteus mirabilis, Pseudomonas aeruginosa, Streptococcus contellatus, S. intermedius; complicated urinary tract infections; pyelonephritis; and complicated intraabdominal infections. ▪ CONTRAINDICATIONS: Viral infection and known hypersensitivity to this drug or to meropenem, imipenem, penicillin, or beta-lactam prohibit the use of this drug. ▪ ADVERSE EFFECTS: Adverse effects of this drug include headache, diarrhea, nausea, vomiting, urticaria, phlebitis, erythema at the injection site, and pruritis. Life-threatening side effects include seizures, pseudomembranous colitis, hepatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, and anaphylaxis. A common side effect is rash.
