diphtheria and tetanus toxoids (DT), an active immunizing agent. ▪ INDICATIONS: It is prescribed for immunization against diphtheria and tetanus when pertussis vaccination is contraindicated. ▪ CONTRAINDICATIONS: Immunosuppression, acute infection, or concomitant use of corticosteroids prohibits its use. ▪ ADVERSE EFFECTS: The most serious adverse reaction is anaphylaxis.