diclofenac /diklo′fenak/ , a nonsteroidal antiinflammatory drug used systemically as the potassium or sodium salt in the treatment of rheumatic and nonrheumatic inflammatory conditions and as the potassium salt to relieve pain and dysmenorrhea. It is also applied topically to the conjunctiva as a sodium salt to reduce ocular inflammation or photophobia after certain kinds of surgery and to the skin to treat actinic keratoses.