dichlorphenamide /dī′klôrfen″əmīd/ , a carbonic anhydrase inhibitor. ▪ INDICATIONS: It is prescribed in the treatment of chronic open-angle glaucoma and before surgery for angle-closure glaucoma. ▪ CONTRAINDICATIONS: Liver and adrenocortical insufficiency, kidney failure, hyperchloremic acidosis, depressed sodium or potassium level, pulmonary obstruction, Addison’s disease, known or suspected pregnancy, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are anorexia, GI disturbances, acidosis, ureteral calculus formation, and aplastic anemia.
