dexmedetomidine, an alpha2 adrenoceptor agonist sedative. ▪ INDICATIONS: It is used to sedate mechanically ventilated and intubated patients in the intensive care unit. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug contraindicates its use. ▪ ADVERSE EFFECTS: Life-threatening effects are atrial fibrillation and infarction. Other serious adverse effects include oliguria, hypertension, pulmonary edema, pleural effusion, hypoxia, leukocytosis, and anemia. Common side effects include nausea, bradycardia, and hypotension.
