demecarium bromide /dē′məker″ē·əm/ , an ophthalmic anticholinesterase agent. ▪ INDICATIONS: It is prescribed in the treatment of open-angle glaucoma. ▪ CONTRAINDICATIONS: Active uveal inflammation and/or glaucoma associated with iridocyclitis, bronchial asthma, peptic ulcer, epilepsy, recent myocardial infarction, pregnancy, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are bradycardia, diarrhea, eye irritation, hypotension, headache, formation of cysts, and lens opacities.
